VERMALAB

 

CARDIOMETABOLIC RESEARCH

2012

  

Yanagawa B, Lovren F, Pan Y, Garg V, Quan A, Tang G, Singh KK, Shukla PC, Kalra NP, Peterson MD, Verma S.

miRNA-141 is a novel regulator of BMP-2-mediated calcification in aortic stenosis.

J Thorac Cardiovasc Surg. 2012 Feb 13. (in press)

 

Gupta M, Singh N, Tsigoulis M, Kajil M, Hirjikaka S, Quan A, Teoh H, Verma S.  

Perceptions of Canadian primary care physicians towards cardiovascular risk assessment and lipid management.

Can J Cardiol. 2012 Jan-Feb;28(1):14-9.

 

Teoh H, Quan A, Creighton AK, Annie Bang KW, Singh KK, Shukla PC, Gupta N, Pan Y, Lovren F, Leong-Poi H, Al-Omran M, Verma S.

BRCA1 gene therapy reduces systemic inflammatory response and multiple organ failure and improves survival in experimental sepsis.

Gene Ther. 2012 Jan 19. (in press)

 

Singh KK, Shukla PC, Quan A, Desjardins JF, Lovren F, Pan Y, Garg V, Gosal S,  Garg A, Szmitko PE, Schneider MD, Parker TG, Stanford WL, Leong-Poi H, Teoh H, Al-Omran M, Verma S.

BRCA2 Protein Deficiency Exaggerates Doxorubicin-induced Cardiomyocyte Apoptosis and Cardiac Failure.

J Biol Chem. 2012 Feb 24;287(9):6604-14.

 

2011

  

Shukla PC, Singh KK, Quan A, Al-Omran M, Teoh H, Lovren F, Cao L, Rovira II, Pan Y, Brezden-Masley C, Yanagawa B, Gupta A, Deng CX, Coles JG, Leong-Poi H, Stanford WL, Parker TG, Schneider MD, Finkel T, Verma S.

BRCA1 is an essential regulator of heart function and survival following myocardial infarction.

Nat Commun. 2011 Dec 20;2:593.

 

Al-Omran M, Verma S, Lindsay TF.

Suboptimal use of risk reduction therapy in peripheral arterial disease patients at a major teaching hospital.

Ann Saudi Med. 2011 Jul-Aug;31(4):371-5.

 

Singh KK, Shukla PC, Quan A, Lovren F, Pan Y, Wolfstadt JI, Gupta M, Al-Omran M, Leong-Poi H, Teoh H, Verma S.

Herceptin, a recombinant humanized anti-ERBB2 monoclonal antibody, induces cardiomyocyte death.

Biochem Biophys Res Commun. 2011 Jul 29;411(2):421-6.

 

 Al-Mubarak HA, Alamri TM, Aljabab SA, Atteya M, Quan A, Teoh H, Shukla PC, Verma S, Aldahmash A, Aljabri B, Napoli C, Al-Omran M.

Effects on duration of post-operative ischemia and patterns of blood flow recovery in different conditions of mouse hind limb ischemia.

Vasc Cell. 2011 Jun 14;3(1):14.

  

Cardiometabolic Risk Working Group: Executive Committee, Leiter LA, Fitchett DH, Gilbert RE, Gupta M, Mancini GB, McFarlane PA, Ross R, Teoh H, Verma S, Anand S, Camelon K, Chow CM, Cox JL, Després JP, Genest J, Harris SB, Lau DC, Lewanczuk R, Liu PP, Lonn EM, McPherson R, Poirier P, Qaadri S, Rabasa-Lhoret R, Rabkin SW, Sharma AM, Steele AW, Stone JA, Tardif JC, Tobe S, Ur E.

Identification and management of cardiometabolic risk in Canada: a position paper by the cardiometabolic risk working group (executive summary).

Can J Cardiol. 2011 Mar-Apr;27(2):124-31.

  

Verma S, Gupta M, Holmes DT, Xu L, Teoh H, Gupta S, Yusuf S, Lonn EM.

Plasma renin activity predicts cardiovascular mortality in the Heart Outcomes Prevention Evaluation (HOPE) study.

Eur Heart J. 2011 Sep;32(17):2135-42.

  

Anderson TJ, Charbonneau F, Title LM, Buithieu J, Rose MS, Conradson H, Hildebrand K, Fung M, Verma S, Lonn EM.

Microvascular function predicts cardiovascular events in primary prevention: long-term results from the Firefighters and Their Endothelium (FATE) study.

Circulation. 2011 Jan 18;123(2):163-9.

 

Lovren F, Pan Y, Quan A, Singh KK, Shukla PC, Gupta M, Al-Omran M, Teoh H, Verma S.

Adropin is a novel regulator of endothelial function.

Circulation. 2010  Sep 14;122(11 Suppl):S185-92.

 

Lovren F, Pan Y, Quan A, Szmitko PE, Singh KK, Shukla PC, Gupta M, Chan L, Al-Omran M, Teoh H, Verma S.

Adiponectin primes human monocytes into alternative anti-inflammatory M2 macrophages.

Am J Physiol Heart Circ Physiol. 2010 Sep;299(3):H656-63.

 

Gupta M, Szmitko PE, Tsigoulis M, Braga MF, Kajil M, Herjikaka S, Quan A, Teoh H, Verma S.

Effects of ezetimibe add-on to statin therapy on adipokine production in patients with metabolic syndrome and stable vascular disease.

J Cardiovasc Pharmacol. 2010 Sep;56(3):241-5.

 

Shukla PC, Singh KK, Yanagawa B, Teoh H, Verma S.

DNA damage repair and cardiovascular diseases.

Can J Cardiol. 2010 Mar;26 Suppl A:13A-16A.

  

2010

 

Shukla PC, Singh KK, Yanagawa B, Teoh H, Verma S

DNA Damage Repair and Cardiovascular Diseases.

Can J Cardiol.  (in press)

 

Szmitko PE, Leiter LA, Verma S

The incretin system and cardiometabolic disease.

Can J Cardiol 2010: 26: 87-95.

 

2009

 

Verma S, Mesana TG

Mitral-valve repair for mitral-valve prolapse.

N Engl J Med 2009: 361: pp 2261-9.

 

Fitchett D, Eikelboom J, Fremes A, Mazer S, Singh A, Bittira B, Brister A, Graham JJ, Gupta M, Karkouti K, Lee A, Love M, McArthur R, Peterson M, Verma S, Yau, TM

Dual antiplatelet therapy in patients requiring urgent coronary artery bypass grafting surgery: A position statement of the Canadian Cardiovascular Society.

Can J Cardiol: 2009: 25(12): pp 683-9.

 

MV Badiwala, S Verma, V Rao

Surgical Management of Ischemic Mitral Regurgitation.

Circulation: 2009: 120(13): pp 1287-93.

 

Philpott AC, Lonn E, Title LM, Verma S, Buithieu J, Charbonneau F, Anderson TJ.

Comparison of new measures of vascular function to flow mediated dilatation as a measure of cardiovascular risk factors.

Am J Cardiol. 2009 Jun 1;103(11):1610-5..

 

Chan CT, Lovren F, Pan Y, Verma S.

Nocturnal haemodialysis is associated with improved vascular smooth muscle cell biology.

Nephrol Dial Transplant. 2009: 24(12): pp 3867-71.

 

Yan RT, Yan AT, Anderson TJ, Buithieu J, Charbonneau F, Title L, Verma S, Lonn EM.

The differential association between various anthropometric indices of obesity and subclinical atherosclerosis.

Atherosclerosis. 2009 Apr 16. [Epub ahead of print]

 

Kuo LT, Chen SJ, Cherng WJ, Yang NI, Lee CC, Cheng CW, Verma S, Wang CH.

Late reperfusion of a totally occluded infarct-related artery increases granulocyte-colony stimulation factor and reduces stroma-derived factor-1alpha blood levels in patients with ongoing ischemia after acute myocardial infarction.

Int Heart J. 2009 Jul;50(4):433-44.

 

Verma S, Lonn EM, Nanji A, Browne K, Ward R, Robertson A, Conradson H, Hildebrand K, Brant R, Anderson TJ.

Effect of angiotensin-converting enzyme inhibition on C-reactive protein levels: the ramipril C-reactive pRotein randomized evaluation (4R) trial results.

Can J Cardiol. 2009 Jul;25(7):e236-40.

 

Gupta M, Braga MF, Teoh H, Tsigoulis M, Verma S.

Statin effects on LDL and HDL cholesterol in South Asian and white populations.

J Clin Pharmacol. 2009 Jul;49(7):831-7.

 

Lovren F, Pan Y, Shukla PC, Quan A, Teoh H, Szmitko PE, Peterson MD, Gupta M, Al-Omran M, Verma S.

Visfatin activates eNOS via Akt and MAP kinases and improves endothelial cell function and angiogenesis in vitro and in vivo: translational implications for atherosclerosis.

Am J Physiol Endocrinol Metab. 2009 Jun;296(6):E1440-9.

 

Desjardins JF, Pourdjabbar A, Quan A, Leong-Poi H, Teichert-Kuliszewska K, Verma S, Parker TG.

Lack of S100A1 in mice confers a gender-dependent hypertensive phenotype and increased mortality after myocardial infarction.

Am J Physiol Heart Circ Physiol. 2009 May;296(5):H1457-65.

 

Jialal I, Verma S, Devaraj S.

Inhibition of endothelial nitric oxide synthase by C-reactive protein: clinical relevance.

Clin Chem. 2009 Feb;55(2):206-8.

 

2008

 

Title LM, Lonn E, Charbonneau F, Fung M, Mather KJ, Verma S, Anderson TJ.

Relationship between brachial artery flow-mediated dilatation, hyperemic shear stress, and the metabolic syndrome.

Vasc Med. 2008 Nov;13(4):263-70.

 

Gupta M, Braga MB, Verma S.

A randomized, controlled trial of the effects of rosiglitazone on adipokines, and inflammatory and fibrinolytic markers in diabetic patients: study design and protocol.

Can J Cardiol. 2008 Oct;24(10):e65-9.

 

Kuo LT, Yang NI, Cherng WJ, Verma S, Hung MJ, Wang SY, Liu MH, Chen SY, Wang CH.

Serum interleukin-6 levels, not genotype, correlate with coronary plaque complexity.

Int Heart J. 2008 Jul;49(4):391-402.

 

Lovren F, Pan Y, Quan A, Teoh H, Wang G, Shukla PC, Levitt KS, Oudit GY, Al-Omran M, Stewart DJ, Slutsky AS, Peterson MD, Backx PH, Penninger JM, Verma S.

Angiotensin converting enzyme-2 confers endothelial protection and attenuates atherosclerosis.

Am J Physiol Heart Circ Physiol. 2008 Oct;295(4):H1377-84.

 

Verma S, Gupta MK.

Aliskiren improves nitric oxide bioavailability and limits atherosclerosis.

Hypertension. 2008 Sep;52(3):467-9.

 

Teoh H, Quan A, Bang KW, Wang G, Lovren F, Vu V, Haitsma JJ, Szmitko PE, Al-Omran M, Wang CH, Gupta M, Peterson MD, Zhang H, Chan L, Freedman J, Sweeney G, Verma S.

Adiponectin deficiency promotes endothelial activation and profoundly exacerbates sepsis-related mortality.

Am J Physiol Endocrinol Metab. 2008 Sep;295(3):E658-64.

 

Al-Omran M, Mamdani MM, Lindsay TF, Melo M, Juurlink DN, Verma S; Systematic Assessment of Vascular Risk Investigators.

Suboptimal use of statin therapy in elderly patients with atherosclerosis: a population-based study.

J Vasc Surg. 2008 Sep;48(3):607-12.

 

Szmitko PE, Verma S.

The endocannabinoid system and cardiometabolic risk.

Atherosclerosis. 2008 Aug;199(2):248-56.

 

Teoh H, Quan A, Lovren F, Wang G, Tirgari S, Szmitko PE, Szalai AJ, Ward ME, Verma S.

Impaired endothelial function in C-reactive protein overexpressing mice.

Atherosclerosis. 2008 Dec;201(2):318-25.

 

  

Kim BO, Verma S, Weisel RD, Fazel S, Jia ZQ, Mizuno T, Li RK.

Preservation of heart function in diabetic rats by the combined effects of muscle cell implantation and insulin therapy.

Eur J Heart Fail. 2008 Jan;10(1):14-21.

 

Wang CH, Cherng WJ, Yang NI, Hsu CM, Yeh CH, Lan YJ, Wang JS, Verma S.

Cyclosporine increases ischemia-induced endothelial progenitor cell mobilization through manipulation of the CD26 system.

Am J Physiol Regul Integr Comp Physiol. 2008 Mar;294(3):R811-8.

 

2007

 

Teoh H, Verma S.

C-reactive protein, metabolic syndrome, and end organ damage.

Metabolism. 2007 Dec;56(12):1620-2.

 

Gupta M, Verma S, Mancini GB.

ACE inhibitors: back to prime time?

Heart. 2007 Sep;93(9):1015-6.

 

Teoh H, Quan A, Verma S.

Does C-reactive protein predict saphenous vein graft patency?

J Thorac Cardiovasc Surg. 2007 Aug;134(2):277-9.

 

Szmitko PE, Verma S.

C-reactive protein and reendothelialization: NO involvement.

Circ Res. 2007 May 25;100(10):1405-7.

 

Verma S, Slutsky AS.

Idiopathic pulmonary fibrosis--new insights.

N Engl J Med. 2007 Mar 29;356(13):1370-2.

 

Teoh H, Lovren F, Verma S.

Vascular dysfunction: a Janus face of visfatin in diabetes?

Metabolism. 2007 Apr;56(4):459-61.

 

Verma S, Feindel CM.

Skeletonized internal thoracic arteries for CABG surgery: a new gold standard?

Nat Clin Pract Cardiovasc Med. 2007 Apr;4(4):188-9.

 

Szmitko PE, Teoh H, Stewart DJ, Verma S.

Adiponectin and cardiovascular disease: state of the art?

Am J Physiol Heart Circ Physiol. 2007 Apr;292(4):H1655-63. Review.

 

Wang CH, Verma S, Hsieh IC, Hung A, Cheng TT, Wang SY, Liu YC, Stanford WL, Weisel RD, Li RK, Cherng WJ.

Stem cell factor attenuates vascular smooth muscle apoptosis and increases intimal hyperplasia after vascular injury.

Arterioscler Thromb Vasc Biol. 2007 Mar;27(3):540-7.

 

Brister SJ, Hamdulay Z, Verma S, Maganti M, Buchanan MR.

Ethnic diversity: South Asian ethnicity is associated with increased coronary artery bypass grafting mortality.

J Thorac Cardiovasc Surg. 2007 Jan;133(1):150-4.