Hwee Teoh
Senior Research
Associate
PhD
416-864-6060 x77626
teohh@smh.ca
After completing a PhD in
Neuropharmacology at the School of Pharmacy,
University of London Dr. Hwee Teoh carried out
postdoctoral studies at the National University of
Singapore and the University of Hong Kong before
joining St Michael’s Hospital as a Research
Associate. Dr. Teoh’s current research
interests are directed at uncovering how proteins
which are typically involved in non-inflammatory
physiology may contribute to and/or regulate the
body’s innate responses to sepsis insult.
Additionally, she has collaborative links with
several ongoing provincial and national trials that
delve into care management of patients with
cardiovascular, endocrinology and cardiometabolic
disorders.
Select Publications :
Teoh H, Quan A, Creighton AK, Annie Bang KW, Singh KK, Shukla PC, Gupta N, Pan Y, Lovren F, Leong-Poi H, Al-Omran M, Verma S.
BRCA1 gene therapy reduces systemic inflammatory response and multiple organ failure and improves survival in experimental sepsis.
Gene Ther. 2012 Jan 19. doi: 10.1038/gt.2011.214.
Shukla PC, Singh KK, Quan A, Al-Omran M, Teoh H, Lovren F, Cao L, Rovira II, Pan Y, Brezden-Masley C, Yanagawa B, Gupta A, Deng CX, Coles JG, Leong-Poi H, Stanford WL, Parker TG, Schneider MD, Finkel T, Verma S.
BRCA1 is an essential regulator of heart function and survival following myocardial infarction.
Nat Commun. 2011 Dec 20;2:593.
Cardiometabolic Risk Working Group:
Executive Committee, Leiter LA, Fitchett DH, Gilbert RE, Gupta M,
Mancini GB, McFarlane PA, Ross R, Teoh H, Verma S,
Anand S, Camelon K, Chow CM, Cox JL, Després JP, Genest J, Harris
SB, Lau DC, Lewanczuk R, Liu PP, Lonn EM, McPherson R, Poirier P,
Qaadri S, Rabasa-Lhoret R, Rabkin SW, Sharma AM, Steele AW, Stone
JA, Tardif JC, Tobe S, Ur E.
Identification and management of
cardiometabolic risk in
Can J Cardiol. 2011 Mar-Apr;27(2):124-31.
Lovren F, Pan Y, Quan A, Singh KK, Shukla PC, Gupta M, Al-Omran M, Teoh H, Verma S.
Adropin is a novel regulator of endothelial function
Circulation. 2010 Sep 14;122(11 Suppl):S185-92.
Teoh H, Mendelsohn
AA, Goodman SG, Jaffer S, Chen RY, Tjia S, Theriault L, Langer A,
Leiter LA; Guidelines Based Undertaking for Improvement in
Dyslipidemia Related Events (GUIDE) Investigators.
Usefulness of statin-ezetimibe combination to
reduce the care gap in dyslipidemia management in patients with a high
risk of atherosclerotic disease.
Am J Cardiol. 2009 Sep 15;104(6):798-804.
Gupta M,
Statin effects on LDL and HDL cholesterol in
South Asian and white populations.
J Clin Pharmacol. 2009 Jul;49(7):831-7.
Teoh H, Quan A,
Leung SW, Man RY.
Vascular effects of estrone and
diethylstilbestrol in porcine coronary arteries.
Menopause. 2009 Jan-Feb;16(1):104-9.
Lovren F, Pan Y, Quan A, Teoh H,
Wang G, Shukla PC, Levitt KS, Oudit GY, Al-Omran M, Stewart DJ,
Slutsky AS, Peterson MD, Backx PH, Penninger JM, Verma S.
Angiotensin converting enzyme-2 confers
endothelial protection and attenuates atherosclerosis.
Am J Physiol Heart Circ Physiol. 2008
Oct;295(4):H1377-84.
Teoh H , Quan A,
Bang KW, Wang G, Lovren F, Vu V, Haitsma JJ, Szmitko PE, Al-Omran M,
Wang CH, Gupta M, Peterson MD, Zhang H, Chan L, Freedman J, Sweeney
G, Verma S.
Adiponectin deficiency promotes endothelial
activation and profoundly exacerbates sepsis-related mortality.
Am J Physiol Endocrinol Metab. 2008
Sep;295(3):E658-64.
Teoh H, Quan A,
Lovren F, Wang G, Tirgari S, Szmitko PE, Szalai AJ, Ward ME, Verma
S.
Impaired endothelial function in C-reactive
protein overexpressing mice.
Atherosclerosis. 2008 Dec;201(2):318-25.
Does C-reactive protein predict
saphenous vein graft patency?
Teoh H, Quan A, Verma S.
J Thorac Cardiovasc Surg. 2007
Aug;134(2):277-9.
Ward ME, Toporsian M, Scott JA, Teoh
H, Govindaraju V, Quan A, Wener AD, Wang G, Bevan SC, Newton DC,
Marsden PA.
Hypoxia induces a functionally significant
and translationally efficient neuronal NO synthase mRNA variant.
J Clin Invest. 2005 Nov;115(11):3128-39.